Source details
- Authors
- Caroline Aguilera Stewart et al.
- Journal or source
- Nature Communications
- Year
- 2026
- DOI or authoritative URL
- 10.1038/s41467-026-73979-0
- Study type
- Experimental mechanistic study
- Population or material studied
- Experimental skin-expansion models examining fibroblast and epidermal stem-cell signaling.
- Major findings
- Reports a stretch-responsive fibroblast program associated with epidermal stem-cell self-renewal during expansion.
- Limitations
- Mechanistic experimental work; it does not test foreskin restoration or define a safe or effective human protocol.
- Relevance to restoration
- Supports biological plausibility or background only. It does not validate a foreskin-restoration device, method, force, duration, or timeline.
- Source-review status
- Full text reviewed
- Last reviewed
- 2026-08-11
Reports a stretch-responsive fibroblast program associated with epidermal stem-cell self-renewal during expansion.
Read the limitations
This record is an editorial summary. Follow the DOI or authoritative source, consider the study design and population, and do not generalize beyond what was studied.